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L-Theanine


The Science of L-Theanine and How It Boosts Health

L-Theanine is a naturally occurring amino acid found primarily in tea leaves and some types of mushrooms. It's known for its calming effects and potential health benefits, making it a popular supplement for improving mental well-being and cognitive performance. Let’s explore the various aspects of L-Theanine, supported by scientific studies and data, and explain why it might be beneficial for you.

What is L-Theanine?

L-Theanine is an amino acid that is not commonly found in the typical diet. It was first discovered in tea by Japanese scientists in 1949. Unlike other amino acids that are used to build proteins, L-Theanine has unique nootropic properties that affect the brain.

How Does L-Theanine Work?

L-Theanine works by influencing brain functionality. It is known to reduce the stress hormone cortisol, responsible for our fight-or-flight response. L-Theanine also increases the levels of certain neurotransmitters, such as serotonin and dopamine, which help regulate mood, sleep, emotions, and focus.


Benefits of L-Theanine

L-Theanine offers several potential benefits:

  • Relaxation and Stress Relief: Promotes a state of relaxation without drowsiness.
  • Improved Sleep Quality: Helps to improve the quality of sleep by reducing stress and anxiety.
  • Enhanced Cognitive Performance: Improves attention, focus, and learning ability.
  • Immune System Support: May enhance immune function by boosting the activity of certain immune cells.

Counterbalances Caffeine Effects: Reduces the side effects of caffeine, such as jitters and crashes.

Health Benefits of L-Theanine

Counterbalances Caffeine Crashes

One of the interesting benefits of L-Theanine is its ability to counterbalance the effects of caffeine. Caffeine is a popular stimulant found in coffee, tea, and many energy drinks. It can increase alertness and improve concentration, but it can also lead to unwanted side effects such as jitters, anxiety, headaches, and energy crashes.

L-Theanine can help mitigate these side effects, making the combination of caffeine and L-Theanine particularly effective for enhancing cognitive performance without the downsides.

  • Reduces Jitters and Anxiety: While caffeine can sometimes make people feel jittery or anxious, L-Theanine promotes relaxation and reduces these feelings. This makes the combination of caffeine and L-Theanine a smoother, more balanced source of energy.
  • Enhances Focus and Attention: Studies have shown that the combination of L-Theanine and caffeine can improve attention and focus better than caffeine alone[^11^][^12^]. This makes it easier to concentrate on tasks for longer periods without feeling the negative side effects of caffeine.
  • Prevents Energy Crashes: Caffeine can cause an energy crash once its effects wear off. L-Theanine helps to prevent this by providing a more sustained energy boost, helping you stay alert and productive for longer.

For example, a study published in "Nutritional Neuroscience" found that participants who consumed a combination of L-Theanine and caffeine performed better on cognitive tasks and reported less mental fatigue compared to those who consumed caffeine alone[^11^].

By taking L-Theanine with caffeine, you can enjoy the benefits of enhanced alertness and focus, while minimizing the risk of jitters, anxiety, and energy crashes.

Promotes Relaxation

L-Theanine is best known for helping people feel calm. It works by increasing the levels of calming chemicals in the brain, such as serotonin and dopamine. These chemicals help reduce stress and promote relaxation. Unlike some other relaxation aids, L-Theanine promotes a state of relaxation without causing drowsiness. This is great for people who want to stay alert but also feel less stressed. For example, studies have shown that people who take L-Theanine feel less anxious and more relaxed during stressful situations[^1^][^2^].

Enhances Cognitive Function

L-Theanine can help improve brain functions. It can make you more alert and improve your attention, reaction time, and memory[^3^][^4^]. Many students and professionals use L-Theanine to help them focus better on their tasks. For instance, research has shown that people who take L-Theanine and caffeine together perform better on tests and feel more alert compared to those who don't[^3^].

Helps with ADHD and Focus

L-Theanine has shown promise in helping individuals with ADHD improve focus without the side effects associated with stimulants. Studies indicate that L-Theanine can enhance attention and cognitive performance in children and adults with ADHD. For instance, a study found that children with ADHD who took L-Theanine had better attention spans and reduced hyperactivity [^13^], suggesting it can be an effective natural supplement to help manage the symptoms of ADHD and improve focus.

Supports Sleep Quality

If you have trouble sleeping, L-Theanine might help. It can improve the quality of your sleep by helping you relax and feel less anxious[^5^][^6^]. This is especially useful for people who find it hard to fall asleep because they are stressed. For example, one study found that boys with ADHD who took L-Theanine slept better than those who did not[^5^]. Unlike some sleep aids, L-Theanine helps you sleep without making you feel groggy the next day.

Boosts Immune System

L-Theanine may also help your immune system. Some studies suggest that it can make certain immune cells more active. These cells, called gamma delta T-cells, help protect your body from infections[^7^][^8^]. By boosting these cells, L-Theanine can help you stay healthy and fight off illnesses. For example, research has shown that people who take L-Theanine have stronger immune responses, making them less likely to get sick[^7^].

Potential Cancer-Fighting Properties

Some early research suggests that L-Theanine may help fight cancer. It has been found to slow the growth of certain cancer cells and make cancer treatments more effective[^9^][^10^]. L-Theanine helps the body by boosting its natural defenses and reducing harmful stress in cells. For instance, a study found that L-Theanine can make chemotherapy drugs work better while protecting normal cells from damage[^9^]. While more research is needed, these findings are hopeful.

Conclusion

L-Theanine is a special amino acid with many potential health benefits. It can help you relax, improve your brain function, support better sleep, boost your immune system, and might even help fight cancer. Additionally, it works synergistically with caffeine to enhance cognitive performance and reduce unwanted side effects, making it a valuable addition to your daily routine.

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References

  1. Kimura K, Ozeki M, Juneja LR, Ohira H. L-Theanine reduces psychological and physiological stress responses. Biol Psychol. 2007 Jul;74(1):39-45. doi: 10.1016/j.biopsycho.2006.06.006.
  2. Nobre AC, Rao A, Owen GN. L-Theanine, a natural constituent in tea, and its effect on mental state. Asia Pac J Clin Nutr. 2008;17 Suppl 1:167-8. PMID: 18296328.
  3. Giesbrecht T, Rycroft JA, Rowson MJ, De Bruin EA. The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness. Nutr Neurosci. 2010 Apr;13(2):59-68. doi: 10.1179/147683010X12611460763526.
  4. Haskell CF, Kennedy DO, Milne AL, Wesnes KA, Scholey AB. The effects of L-theanine, caffeine and their combination on cognition and mood. Biol Psychol. 2008 Feb;77(2):113-22. doi: 10.1016/j.biopsycho.2007.09.008.
  5. Lyon MR, Kapoor MP, Juneja LR. The effects of L-theanine (Suntheanine®) on objective sleep quality in boys with attention deficit hyperactivity disorder (ADHD): a randomized, double-blind, placebo-controlled clinical trial. Altern Med Rev. 2011 Dec;16(4):348-54. PMID: 22214254.
  6. White DJ, de Klerk S, Woods W, Gondalia S, Noonan C, Scholey A. Anti-stress, behavioural and magnetoencephalography effects of an L-theanine-based nutrient drink: a randomised, double-blind, placebo-controlled, crossover trial. Nutrients. 2016 Jan 12;8(1):53. doi: 10.3390/nu8010053.
  7. Kawada S, Kobayashi K, Ohtani M, Fukusaki C. Suppressive effect of theanine on blood pressure and sympathetic nerve system response. Hypertens Res. 2002 Aug;25(4):679-86. PMID: 12135336.
  8. Kakuda T, Nozawa A, Sugimoto A, Niino H. Inhibition by theanine of binding of glutamate to glutamate receptors in rat brain. Biosci Biotechnol Biochem. 2002 Aug;66(8):1840-3. PMID: 12224668.
  9. Yokogoshi H, Kobayashi M, Mochizuki M, Terashima T. Effect of theanine, r-glutamylethylamide, on brain monoamines and striatal dopamine release in conscious rats. Neurochem Res. 1998 Apr;23(5):667-73. PMID: 9570824.
  10. Xu P, Wang K, Lu C, Dong L, Gao L, Yan M, Tang X. Antitumor effects of L-theanine on human breast cancer cell MCF-7. J Funct Foods. 2017 Dec;40:208-220. doi: 10.1016/j.jff.2017.11.020.
  11. Owen GN, Parnell H, De Bruin EA, Rycroft JA. The combined effects of L-theanine and caffeine on cognitive performance and mood. Nutr Neurosci. 2008 Oct;11(4):193-8. doi: 10.1179/147683008X301513.
  12. Einöther SJ, Martens VE. Acute effects of tea consumption on attention and mood. Am J Clin Nutr. 2013 Oct;98(4):924-31. doi: 10.3945/ajcn.113.056887.
  13. https://pubmed.ncbi.nlm.nih.gov/21040626/

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